To design is to converse with what evolution has already written.
About
I am an undergraduate in Biological Sciences at Zhejiang University, currently a research intern at the Walter and Eliza Hall Institute through the InSPIRE program, working on CAR-T receptor design.
I work on protein and enzyme design, molecular dynamics, and the multi-omics side of disease biology — above all at the point where a computational prediction has to survive contact with a bench experiment.
At WEHI I am supervised by Dr. Emma Petley in the labs of Prof. Matt Call and A/Prof. Melissa Call, testing whether a costimulatory receptor rebuilt into its native trimeric form makes T cells activate better.
At Zhejiang University I work with Dr. Yangwei Jiang in Prof. Ruhong Zhou’s lab on enzyme design — we redesigned the rate-limiting enzyme of astaxanthin biosynthesis and confirmed the prediction at the bench — and with Dr. Wenbin Zhou in Prof. Meihua Sui’s lab on the multi-omics basis of sex-biased liver cancer. I was Technical Lead of ZJU-China’s iGEM 2025 team, LumaManta.
This autumn I will spend a semester at the Chinese University of Hong Kong on the IASP exchange.
Sep 2026 — Dec 2026
Exchange Student, International Asian Studies Programme (IASP)
Projects
WEHI
Call Lab
2026
Ongoing
Redesigning a CAR-T costimulatory transmembrane domain back into its native trimeric form, screened by 2 µs MD and validated by flow cytometry and degranulation assays.
ZJU
Zhou Lab
2025
OngoingCombining Rosetta FuncLib with protein language models to redesign the rate-limiting astaxanthin ketolase, validated in vitro at +46.7% yield.
iGEM 2025
Chen Lab
2025
Silver MedalConverting two light inputs into four sensor proteins on demand with CRISPR logic gates, packaged as an all-in-one device for water pollutant and eDNA monitoring.
ZJU Medicine
Sui Lab
2025Tracing sex-biased metabolites across 174 mice from hepatitis through cirrhosis to HCC, then reversing them with estrogen supplementation.
ZJU
Chen Lab
2025
OutstandingEngineering vioE activity and pathway flux for pigment yield, with light- and quorum-controlled circuits that make the output switchable.
2026
WEHI
Call Lab
2026
Ongoing
Redesigning a CAR-T costimulatory transmembrane domain back into its native trimeric form, screened by 2 µs MD and validated by flow cytometry and degranulation assays.
2025
ZJU
Zhou Lab
2025
OngoingCombining Rosetta FuncLib with protein language models to redesign the rate-limiting astaxanthin ketolase, validated in vitro at +46.7% yield.
iGEM 2025
Chen Lab
2025
Silver MedalConverting two light inputs into four sensor proteins on demand with CRISPR logic gates, packaged as an all-in-one device for water pollutant and eDNA monitoring.
ZJU Medicine
Sui Lab
2025Tracing sex-biased metabolites across 174 mice from hepatitis through cirrhosis to HCC, then reversing them with estrogen supplementation.
ZJU
Chen Lab
2025
OutstandingEngineering vioE activity and pathway flux for pigment yield, with light- and quorum-controlled circuits that make the output switchable.
bioinformatics
ZJU Medicine
Sui Lab
2025Tracing sex-biased metabolites across 174 mice from hepatitis through cirrhosis to HCC, then reversing them with estrogen supplementation.
cancer biology
ZJU Medicine
Sui Lab
2025Tracing sex-biased metabolites across 174 mice from hepatitis through cirrhosis to HCC, then reversing them with estrogen supplementation.
enzyme engineering
ZJU
Zhou Lab
2025
OngoingCombining Rosetta FuncLib with protein language models to redesign the rate-limiting astaxanthin ketolase, validated in vitro at +46.7% yield.
igem
iGEM 2025
Chen Lab
2025
Silver MedalConverting two light inputs into four sensor proteins on demand with CRISPR logic gates, packaged as an all-in-one device for water pollutant and eDNA monitoring.
metabolic engineering
ZJU
Chen Lab
2025
OutstandingEngineering vioE activity and pathway flux for pigment yield, with light- and quorum-controlled circuits that make the output switchable.
molecular dynamics
WEHI
Call Lab
2026
Ongoing
Redesigning a CAR-T costimulatory transmembrane domain back into its native trimeric form, screened by 2 µs MD and validated by flow cytometry and degranulation assays.
ZJU
Zhou Lab
2025
OngoingCombining Rosetta FuncLib with protein language models to redesign the rate-limiting astaxanthin ketolase, validated in vitro at +46.7% yield.
multi-omics
ZJU Medicine
Sui Lab
2025Tracing sex-biased metabolites across 174 mice from hepatitis through cirrhosis to HCC, then reversing them with estrogen supplementation.
optogenetics
iGEM 2025
Chen Lab
2025
Silver MedalConverting two light inputs into four sensor proteins on demand with CRISPR logic gates, packaged as an all-in-one device for water pollutant and eDNA monitoring.
protein design
ZJU
Zhou Lab
2025
OngoingCombining Rosetta FuncLib with protein language models to redesign the rate-limiting astaxanthin ketolase, validated in vitro at +46.7% yield.
protein engineering
WEHI
Call Lab
2026
Ongoing
Redesigning a CAR-T costimulatory transmembrane domain back into its native trimeric form, screened by 2 µs MD and validated by flow cytometry and degranulation assays.
srtp
ZJU
Chen Lab
2025
OutstandingEngineering vioE activity and pathway flux for pigment yield, with light- and quorum-controlled circuits that make the output switchable.
structural biology
WEHI
Call Lab
2026
Ongoing
Redesigning a CAR-T costimulatory transmembrane domain back into its native trimeric form, screened by 2 µs MD and validated by flow cytometry and degranulation assays.
synthetic biology
iGEM 2025
Chen Lab
2025
Silver MedalConverting two light inputs into four sensor proteins on demand with CRISPR logic gates, packaged as an all-in-one device for water pollutant and eDNA monitoring.
ZJU
Chen Lab
2025
OutstandingEngineering vioE activity and pathway flux for pigment yield, with light- and quorum-controlled circuits that make the output switchable.
Selected Honors
2026
Oct 2025
Aug 2025
Mar 2026
Gold Medal, 18th "Dandelion" Undergraduate Innovation Competition
CTO — LumaManta eDNA-based aquatic pathogen detectionJan 2025
First Prize (Champion), National Pet Industry Innovation Competition
Led the “Pet Smart Health” team2025
Provincial SRTP Research Grant — rated Outstanding
12,000 RMB2023 – 2025
Academic Honors & Scholarships
- Professional Excellence Scholarship (2023–2024)
- Second-Class Scholarship (2024–2025)
- Innovation & Entrepreneurship Model (2024–2025)
- Academic Excellence Model (2024–2025)
Jun 2025
5th Place, Stand-Up Paddleboard 200 m